Polymorphic Variation in Cytochrome Oxidase Subunit Genes

Cytochrome oxidase (COX) activity varies between individuals and low activities associate with Alzheimer’s disease. Whether genetic heterogeneity influences function of this multimeric enzyme is unknown. To explore this we sequenced 3 mitochondrial DNA (mtDNA) and 10 nuclear COX subunit genes from a...

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Detalhes bibliográficos
Main Authors: Lu, Jianghua, Wang, Kaixuan, Rodova, Mariana, Esteves, Raquel, Berry, Diana, Lezi, E, Crafter, Adam, Barrett, Matthew, Cardoso, Sandra M., Onyango, Isaac, Parker, W. Davis, Fontes, Joseph, Burns, Jeffrey M., Swerdlow, Russell H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2910218/
https://ncbi.nlm.nih.gov/pubmed/20413852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2010-100123
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