Epigenetic inactivation of TWIST2 in acute lymphoblastic leukemia modulates proliferation, cell survival and chemosensitivity

BACKGROUND: Altered regulation of many transcription factors has been shown to be important in the development of leukemia. TWIST2 modulates the activity of a number of important transcription factors and is known to be a regulator of hematopoietic differentiation. Here, we investigated the signific...

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Detaylı Bibliyografya
Asıl Yazarlar: Thathia, Shabnam H., Ferguson, Stuart, Gautrey, Hannah E., van Otterdijk, Sanne D., Hili, Michela, Rand, Vikki, Moorman, Anthony V., Meyer, Stefan, Brown, Robert, Strathdee, Gordon
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Ferrata Storti Foundation 2012
Konular:
Original Articles and Brief Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291591/
https://ncbi.nlm.nih.gov/pubmed/22058208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.049593
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