A risk of essential thrombocythemia in carriers of constitutional CHEK2 gene mutations

Germline mutations of the CHEK2 gene have been reported in some myeloid and lymphoid malignancies, but their impact on development of essential thrombocythemia has not been studied. In 16 out of 106 (15.1%) consecutive patients, newly diagnosed with essential thrombocythemia, we found one of four an...

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Detalhes bibliográficos
Main Authors: Janiszewska, Hanna, Bąk, Aneta, Pilarska, Maria, Heise, Marta, Junkiert-Czarnecka, Anna, Kuliszkiewicz-Janus, Małgorzata, Całbecka, Małgorzata, JaŸwiec, Bożena, Wołowiec, Dariusz, Kuliczkowski, Kazimierz, Haus, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2012
Assuntos:
Original Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291590/
https://ncbi.nlm.nih.gov/pubmed/22058216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.049494
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