A risk of essential thrombocythemia in carriers of constitutional CHEK2 gene mutations

Germline mutations of the CHEK2 gene have been reported in some myeloid and lymphoid malignancies, but their impact on development of essential thrombocythemia has not been studied. In 16 out of 106 (15.1%) consecutive patients, newly diagnosed with essential thrombocythemia, we found one of four an...

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Main Authors: Janiszewska, Hanna, Bąk, Aneta, Pilarska, Maria, Heise, Marta, Junkiert-Czarnecka, Anna, Kuliszkiewicz-Janus, Małgorzata, Całbecka, Małgorzata, JaŸwiec, Bożena, Wołowiec, Dariusz, Kuliczkowski, Kazimierz, Haus, Olga
Format: Artigo
Jezik:Inglês
Izdano: Ferrata Storti Foundation 2012
Teme:
Original Articles and Brief Reports
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291590/
https://ncbi.nlm.nih.gov/pubmed/22058216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2011.049494
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