Prevalence of the BRCA1 c.68_69delAG (BIC: 185delAG) mutation in women with breast cancer from north-central Poland and a review of the literature on other regions of the country

AIM OF THE STUDY: Germline mutations in BRCA tumor suppressor genes are strongly associated with breast and ovarian cancer. The lifetime risk of these cancers in women with BRCA1 mutation is 84% and 27%, respectively. Studies on the prevalence of BRCA1 c.68_69delAG congenital mutation, the most freq...

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Detalhes bibliográficos
Main Authors: Hartwig, Martyna, Janiszewska, Hanna, Bąk, Aneta, Pilarska, Maria, Heise, Marta, Junkiert-Czarnecka, Anna, Laskowski, Ryszard, Haus, Olga
Formato: Artigo
Idioma:Inglês
Publicado em: Termedia Publishing House 2013
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685350/
https://ncbi.nlm.nih.gov/pubmed/23788959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5114/wo.2013.33767
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