EBV-Encoded LMP1 Upregulates Igκ 3′Enhancer Activity and Igκ Expression in Nasopharyngeal Cancer Cells by Activating the Ets-1 through ERKs Signaling

Accumulating evidence indicates that epithelial cancer cells, including nasopharyngeal carcinoma (NPC) cells, express immunoglobulins (Igs). We previously found that the expression of the kappa light chain protein in NPC cells can be upregulated by the EBV-encoded latent membrane protein 1 (LMP1). I...

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Detalhes bibliográficos
Main Authors: Liu, Haidan, Duan, Zhi, Zheng, Hui, Hu, Duosha, Li, Ming, Tao, Yongguang, Bode, Ann M., Dong, Zigang, Cao, Ya
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291551/
https://ncbi.nlm.nih.gov/pubmed/22396784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032624
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