Activation of the Ig Iα1 promoter by the transcription factor Ets-1 triggers Ig Iα1–Cα1 germline transcription in epithelial cancer cells

Immunoglobulins (Igs) are known to be synthesized and secreted only by B lymphocytes. Class switch recombination (CSR) is a key event that enables B cells to express Igs, and one of the crucial steps for CSR initiation is the germline transcription of Ig genes. Surprisingly, recent studies have demo...

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Detalhes bibliográficos
Main Authors: Duan, Zhi, Zheng, Hui, Xu, San, Jiang, Yiqun, Liu, Haidan, Li, Ming, Hu, Duosha, Li, Wei, Bode, Ann M., Dong, Zigang, Cao, Ya
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4003374/
https://ncbi.nlm.nih.gov/pubmed/24185710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2013.52
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