LMP1-augmented kappa intron enhancer activity contributes to upregulation expression of Ig kappa light chain via NF-kappaB and AP-1 pathways in nasopharyngeal carcinoma cells

BACKGROUND: Expression of kappa gene is under the control of distinct cis-regulatory elements, including the kappa intron enhancer (iE(κ)) and the kappa 3' enhancer (3'E(κ)). The active enhancers and expression of immunoglobulin is generally considered to be restricted to B lymphocytes. Ho...

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Detalhes bibliográficos
Main Authors: Liu, HaiDan, Zheng, Hui, Duan, Zhi, Hu, DuoSha, Li, Ming, Liu, SuFang, Li, ZiJian, Deng, XiYun, Wang, ZhenLian, Tang, Min, Shi, Ying, Yi, Wei, Cao, Ya
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774294/
https://ncbi.nlm.nih.gov/pubmed/19860880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-8-92
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