Mapping and Functional Characterisation of a CTCF-Dependent Insulator Element at the 3′ Border of the Murine Scl Transcriptional Domain

The Scl gene encodes a transcription factor essential for haematopoietic development. Scl transcription is regulated by a panel of cis-elements spread over 55 kb with the most distal 3′ element being located downstream of the neighbouring gene Map17, which is co-regulated with Scl in haematopoietic...

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Detalhes bibliográficos
Main Authors: Follows, George A., Ferreira, Rita, Janes, Mary E., Spensberger, Dominik, Cambuli, Francesco, Chaney, Amy F., Kinston, Sarah J., Landry, Josette R., Green, Anthony R., Göttgens, Berthold
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291548/
https://ncbi.nlm.nih.gov/pubmed/22396734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031484
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