Parkinson's Disease–Associated Kinase PINK1 Regulates Miro Protein Level and Axonal Transport of Mitochondria

Mutations in Pten-induced kinase 1 (PINK1) are linked to early-onset familial Parkinson's disease (FPD). PINK1 has previously been implicated in mitochondrial fission/fusion dynamics, quality control, and electron transport chain function. However, it is not clear how these processes are interc...

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Hauptverfasser: Liu, Song, Sawada, Tomoyo, Lee, Seongsoo, Yu, Wendou, Silverio, George, Alapatt, Philomena, Millan, Ivan, Shen, Alice, Saxton, William, Kanao, Tomoko, Takahashi, Ryosuke, Hattori, Nobutaka, Imai, Yuzuru, Lu, Bingwei
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2012
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3291531/
https://ncbi.nlm.nih.gov/pubmed/22396657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002537
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