The Loss of PGAM5 Suppresses the Mitochondrial Degeneration Caused by Inactivation of PINK1 in Drosophila

PTEN-induced kinase 1 (PINK1), which is required for mitochondrial homeostasis, is a gene product responsible for early-onset Parkinson's disease (PD). Another early onset PD gene product, Parkin, has been suggested to function downstream of the PINK1 signalling pathway based on genetic studies...

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Detalhes bibliográficos
Main Authors: Imai, Yuzuru, Kanao, Tomoko, Sawada, Tomoyo, Kobayashi, Yoshito, Moriwaki, Yasuhiro, Ishida, Yosuke, Takeda, Kohsuke, Ichijo, Hidenori, Lu, Bingwei, Takahashi, Ryosuke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996328/
https://ncbi.nlm.nih.gov/pubmed/21151955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1001229
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