The Nitric Oxide-Cyclic GMP Pathway Regulates FoxO and Alters Dopaminergic Neuron Survival in Drosophila

Activation of the forkhead box transcription factor FoxO is suggested to be involved in dopaminergic (DA) neurodegeneration in a Drosophila model of Parkinson's disease (PD), in which a PD gene product LRRK2 activates FoxO through phosphorylation. In the current study that combines Drosophila g...

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Main Authors: Kanao, Tomoko, Sawada, Tomoyo, Davies, Shireen-Anne, Ichinose, Hiroshi, Hasegawa, Kazuko, Takahashi, Ryosuke, Hattori, Nobutaka, Imai, Yuzuru
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290610/
https://ncbi.nlm.nih.gov/pubmed/22393355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0030958
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