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Detailed mutational analysis of TAR RNA: critical spacing between the bulge and loop recognition domains.
Trans-activation of HIV-1 by the Tat protein is mediated through a cis-acting element (TAR) in the viral RNA. In order to obtain further insight into the molecular interactions for trans-activation, a detailed mutational analysis of TAR RNA was carried out. TAR RNA forms a hairpin structure with imp...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1991
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC329115/ https://ncbi.nlm.nih.gov/pubmed/1956776 |
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