Inhibition of Endothelial Cell Proliferation and Tumor Angiogenesis by Up-Regulating NDRG2 Expression in Breast Cancer Cells

The N-myc downstream-regulated gene 2 (NDRG2) is involved in tumor cell differentiation and apoptosis, but its function in tumor angiogenesis remains to be established. Here, we employed adenovirus overexpressing NDRG2 (Ad-NDRG2) to efficiently up-regulate target gene expression in the NDRG2-low-exp...

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Detalhes bibliográficos
Main Authors: Ma, Ji, Liu, Wenchao, Yan, Xiaohong, Wang, Qianrong, Zhao, Qingli, Xue, Yan, Ren, Hui, Wu, Lin, Cheng, Yuanxiong, Li, Sen, Miao, Lu, Yao, Libo, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290656/
https://ncbi.nlm.nih.gov/pubmed/22393400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0032368
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