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Manipulation of the 'zinc cluster' region of transcriptional activator LEU3 by site-directed mutagenesis.
The transcriptional activator LEU3 of Saccharomyces cerevisiae belongs to a family of lower eukaryotic DNA binding proteins with a well-conserved DNA binding motif known as the Zn(II)2Cys6 binuclear cluster. We have constructed mutations in LEU3 that affect either one of the conserved cysteines (Cys...
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| Veröffentlicht in: | Nucleic Acids Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
1991
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| Online Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC329057/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1945883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/19.21.5991 |
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