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Site-directed mutagenesis of a tRNA gene: base alterations in the coding region affect transcription.
Point mutations have been introduced in vitro in a cloned nematode tRNAPro gene. Four different mutant clones altered in the DNA that codes for tRNAPro have been isolated. Studies on the expression of the mutant genes by microinjection into Xenopus oocyte nuclei reveal that their activities as trans...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1982
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC345978/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6951183/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.79.5.1388 |
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