RNA transcripts serve as a template for double-strand break repair in human cells
Abstract Double-strand breaks (DSBs) are toxic lesions that lead to genome instability. While canonical DSB repair pathways typically operate independently of RNA, growing evidence suggests that RNA:DNA hybrids and nearby transcripts can influence repair outcomes. However, whether transcript RNA can...
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| Principais autores: | , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Portfolio
2025-05-01
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| coleção: | Nature Communications |
| Acesso em linha: | https://doi.org/10.1038/s41467-025-59510-x |
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