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One base pair change abolishes the T cell-restricted activity of a kB-like proto-enhancer element from the interleukin 2 promoter.

The inducible, T cell-specific enhancers of murine and human Interleukin 2 (Il-2) genes contain the kB-like sequence GGGATTTCACC as an essential cis-acting enhancer motif. When cloned in multiple copies this so-called TCEd (distal T cell element) acts as an inducible proto-enhancer element in E14 T...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Briegel, K, Hentsch, B, Pfeuffer, I, Serfling, E
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1991
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC329049/
https://ncbi.nlm.nih.gov/pubmed/1945879
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