The weak, fine-tuned binding of ubiquitous transcription factors to the Il-2 enhancer contributes to its T cell-restricted activity.

The T lymphocyte-specific enhancers of the murine and human Interleukin 2 (Il-2) genes harbour several binding sites for ubiquitous transcription factors. All these sites for the binding of AP-1, NF-kB or Oct-1 are non-canonical sites, i.e. they differ in one or a few base pairs from consensus seque...

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Bibliografische gegevens

Gepubliceerd in:	Nucleic Acids Res
Hoofdauteurs:	Hentsch, B, Mouzaki, A, Pfeuffer, I, Rungger, D, Serfling, E
Formaat:	Artigo
Taal:	Inglês
Gepubliceerd in:	Oxford University Press 1992
Online toegang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336904/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1614851/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/20.11.2657
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