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An Inducible Caspase 9 Suicide Gene to Improve the Safety of Mesenchymal Stromal Cell Therapies

Mesenchymal stromal cells (MSCs) have been infused in hundreds of patients to date, with minimal reported side effects. However, follow-up is limited and long term side effects are unknown. Because several animal models have raised safety concerns, we sought to develop a system allowing control over...

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Detalles Bibliográficos
Main Authors: Ramos, Carlos A., Asgari, Zahra, Liu, Enli, Yvon, Eric, Heslop, Helen E., Rooney, Cliona M., Brenner, Malcolm K., Dotti, Gianpietro
Formato: Artigo
Idioma:Inglês
Publicado: 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290395/
https://ncbi.nlm.nih.gov/pubmed/20506146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.433
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