Rapamycin decreases airway remodeling and hyperreactivity in a transgenic model of noninflammatory lung disease

Airway hyperreactivity (AHR) and remodeling are cardinal features of asthma and chronic obstructive pulmonary disease. New therapeutic targets are needed as some patients are refractory to current therapies and develop progressive airway remodeling and worsening AHR. The mammalian target of rapamyci...

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Bibliografiska uppgifter
Huvudupphovsmän: Kramer, Elizabeth L., Hardie, William D., Mushaben, Elizabeth M., Acciani, Thomas H., Pastura, Patricia A., Korfhagen, Thomas R., Hershey, Gurjit Khurana, Whitsett, Jeffrey A., Le Cras, Timothy D.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Physiological Society 2011
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3290353/
https://ncbi.nlm.nih.gov/pubmed/21903885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/japplphysiol.00737.2011
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