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Effector Functions of Donor-Reactive CD8 Memory T Cells Are Dependent on ICOS Induced During Division in Cardiac Grafts

Alloreactive T-cell memory is present in every transplant recipient and endangers graft survival. Even in the absence of known sensitizing exposures, heterogonous immunity and homeostatic T-cell proliferation generate `endogenous' memory T cells with donor-reactivity. We have recently shown tha...

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Autors principals: Schenk, A. D., Gorbacheva, V., Rabant, M., Fairchild, R. L., Valujskikh, A.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289995/
https://ncbi.nlm.nih.gov/pubmed/18976292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2008.02460.x
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