Effector Functions of Donor-Reactive CD8 Memory T Cells Are Dependent on ICOS Induced During Division in Cardiac Grafts

Alloreactive T-cell memory is present in every transplant recipient and endangers graft survival. Even in the absence of known sensitizing exposures, heterogonous immunity and homeostatic T-cell proliferation generate `endogenous' memory T cells with donor-reactivity. We have recently shown tha...

Full description

Saved in:
Bibliographic Details
Main Authors: Schenk, A. D., Gorbacheva, V., Rabant, M., Fairchild, R. L., Valujskikh, A.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289995/
https://ncbi.nlm.nih.gov/pubmed/18976292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2008.02460.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items