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Effector Functions of Donor-Reactive CD8 Memory T Cells Are Dependent on ICOS Induced During Division in Cardiac Grafts
Alloreactive T-cell memory is present in every transplant recipient and endangers graft survival. Even in the absence of known sensitizing exposures, heterogonous immunity and homeostatic T-cell proliferation generate `endogenous' memory T cells with donor-reactivity. We have recently shown tha...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289995/ https://ncbi.nlm.nih.gov/pubmed/18976292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-6143.2008.02460.x |
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