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Blood-Brain Barrier Abnormalities Caused by HIV-1 gp120: Mechanistic and Therapeutic Implications
The blood-brain barrier (BBB) is compromised in many systemic and CNS diseases, including HIV-1 infection of the brain. We studied BBB disruption caused by HIV-1 envelope glycoprotein 120 (gp120) as a model. Exposure to gp120, whether acute [by direct intra-caudate-putamen (CP) injection] or chronic...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Scientific World Journal
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289936/ https://ncbi.nlm.nih.gov/pubmed/22448134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1100/2012/482575 |
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