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HIV-1 gp120-Induced Injury to the Blood-Brain Barrier: Role of Metalloproteinases 2 and 9 and Relationship to Oxidative Stress
Blood-brain barrier (BBB) disruption occurs during HIV encephalopathy but the mechanisms involved are not understood. We studied how acute and ongoing exposure to HIV-1 envelope gp120 alters BBB structure and permeability. Intravenous Evans Blue, given before stereotaxic gp120 injection into the cau...
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| Publicado no: | J Neuropathol Exp Neurol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4707960/ https://ncbi.nlm.nih.gov/pubmed/20613638 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/NEN.0b013e3181e8c96f |
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