The Genome of Mycobacterium Africanum West African 2 Reveals a Lineage-Specific Locus and Genome Erosion Common to the M. tuberculosis Complex

BACKGROUND: M. africanum West African 2 constitutes an ancient lineage of the M. tuberculosis complex that commonly causes human tuberculosis in West Africa and has an attenuated phenotype relative to M. tuberculosis. METHODOLOGY/PRINCIPAL FINDINGS: In search of candidate genes underlying these diff...

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Main Authors: Bentley, Stephen D., Comas, Iñaki, Bryant, Josephine M., Walker, Danielle, Smith, Noel H., Harris, Simon R., Thurston, Scott, Gagneux, Sebastien, Wood, Jonathan, Antonio, Martin, Quail, Michael A., Gehre, Florian, Adegbola, Richard A., Parkhill, Julian, de Jong, Bouke C.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289620/
https://ncbi.nlm.nih.gov/pubmed/22389744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001552
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