Comparative genomics of Mycobacterium africanum Lineage 5 and Lineage 6 from Ghana suggests distinct ecological niches

Mycobacterium africanum (Maf) causes a substantial proportion of human tuberculosis in some countries of West Africa, but little is known on this pathogen. We compared the genomes of 253 Maf clinical isolates from Ghana, including N = 175 Lineage 5 (L5) and N = 78 Lineage 6 (L6). We found that the g...

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Published in:Sci Rep
Main Authors: Otchere, Isaac Darko, Coscollá, Mireia, Sánchez-Busó, Leonor, Asante-Poku, Adwoa, Brites, Daniela, Loiseau, Chloe, Meehan, Conor, Osei-Wusu, Stephen, Forson, Audrey, Laryea, Clement, Yahayah, Abdallah Iddrisu, Baddoo, Akosua, Ansa, Gloria Akosua, Aboagye, Samuel Yaw, Asare, Prince, Borrell, Sonia, Gehre, Florian, Beckert, Patrick, Kohl, Thomas A., N’dira, Sanoussi, Beisel, Christian, Antonio, Martin, Niemann, Stefan, de Jong, Bouke C., Parkhill, Julian, Harris, Simon R., Gagneux, Sebastien, Yeboah-Manu, Dorothy
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6062541/
https://ncbi.nlm.nih.gov/pubmed/30050166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29620-2
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