The Genome of Mycobacterium Africanum West African 2 Reveals a Lineage-Specific Locus and Genome Erosion Common to the M. tuberculosis Complex

BACKGROUND: M. africanum West African 2 constitutes an ancient lineage of the M. tuberculosis complex that commonly causes human tuberculosis in West Africa and has an attenuated phenotype relative to M. tuberculosis. METHODOLOGY/PRINCIPAL FINDINGS: In search of candidate genes underlying these diff...

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Detalhes bibliográficos
Main Authors: Bentley, Stephen D., Comas, Iñaki, Bryant, Josephine M., Walker, Danielle, Smith, Noel H., Harris, Simon R., Thurston, Scott, Gagneux, Sebastien, Wood, Jonathan, Antonio, Martin, Quail, Michael A., Gehre, Florian, Adegbola, Richard A., Parkhill, Julian, de Jong, Bouke C.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289620/
https://ncbi.nlm.nih.gov/pubmed/22389744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001552
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