TEM8/ANTXR1 Blockade Inhibits Pathological Angiogenesis and Potentiates Tumoricidal Responses against Multiple Cancer Types

Current anti-angiogenic agents used to treat cancer only partially inhibit neovascularization and cause normal tissue toxicities, fueling the need to identify therapeutic agents that are more selective for pathological angiogenesis. Tumor Endothelial Marker 8 (TEM8), also known as anthrax toxin rece...

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Hlavní autoři: Chaudhary, Amit, Hilton, Mary Beth, Seaman, Steven, Haines, Diana C., Stevenson, Susan, Lemotte, Peter K., Tschantz, William R., Zhang, Xiaoyan M., Saha, Saurabh, Fleming, Tony, Croix, Brad St.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289547/
https://ncbi.nlm.nih.gov/pubmed/22340594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2012.01.004
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