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Distinctive immunoregulatory effects of adenosine on T cells of older humans
A role for adenosine in immunosenescence was investigated in T cells from older (≥65 yr) and younger (24–45 yr) healthy humans. Adenosine concentrations in cultures of activated T cells were significantly higher (P<0.0001) for older (145±47 nM, mean±sd) than younger (58±5.5 nM) subjects. Expressi...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Federation of American Societies for Experimental Biology
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289505/ https://ncbi.nlm.nih.gov/pubmed/22121051 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.11-197046 |
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