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Neoplastic "Black Ops": Cancer's Subversive Tactics in Overcoming Host Defenses

Metastatic cancer is usually an incurable disease. Cancers have a broad repertoire of subversive tactics to defeat the immune system. They mimic self, they down-regulate MHC molecules so that T cells are blind to their presence, they interfere with antigen presentation, and they produce factors that...

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Detalhes bibliográficos
Main Authors: Biragyn, Arya, Longo, Dan L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288709/
https://ncbi.nlm.nih.gov/pubmed/22257681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2012.01.005
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