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Synaptic release and extracellular actions of Zn(2+) limit propagation of spreading depression and related events in vitro and in vivo
Cortical spreading depression (CSD) is a consequence of a slowly propagating wave of neuronal and glial depolarization (spreading depolarization; SD). Massive release of glutamate contributes to SD propagation, and it was recently shown that Zn(2+) is also released from synaptic vesicles during SD....
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289481/ https://ncbi.nlm.nih.gov/pubmed/22131381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00453.2011 |
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