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K12/SECTM1, an interferon-γ regulated molecule, synergizes with CD28 to costimulate human T cell proliferation

CD7 is a cell-surface molecule, expressed on T lymphocytes and NK cells, which functions as a costimulatory receptor for T cell proliferation. SECTM1 has been proposed as a ligand for CD7. However, the expression pattern of this molecule in human immune cells and role in human T cell function remain...

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Detalhes bibliográficos
Main Authors: Wang, Tao, Huang, Catherine, Lopez-Coral, Alfonso, Slentz-Kesler, Kimberly A., Xiao, Min, Wherry, E. John, Kaufman, Russel E.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289399/
https://ncbi.nlm.nih.gov/pubmed/22184754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.1011498
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