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IL-10-induced gp130 expression in mouse mast cells permits IL-6 trans-signaling

It is reported that human and mouse mast cells express the IL-27R, which consists of WSX-1 (the IL-27Rα subunit) and the signal-transducing subunit gp130. Although it has been proposed that IL-27 may negatively regulate mast cell-dependent, immediate hypersensitivity responses directly, this has yet...

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Detalhes bibliográficos
Main Authors: Traum, Daniel, Timothee, Patricia, Silver, Jonathan, Rose-John, Stefan, Ernst, Matthias, LaRosa, David F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Leukocyte Biology 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289398/
https://ncbi.nlm.nih.gov/pubmed/22140267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.0411209
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