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IL-6 mediates the susceptibility of gp130 hypermorphs to Toxoplasma gondii

IL-6 and IL-27 are closely related cytokines that play critical, but distinct, roles during infection with Toxoplasma gondii. Thus, IL-6 is required for the development of protective immunity to this pathogen, while IL-27 is required to limit infection-induced pathology. Paradoxically, these factors...

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Hlavní autoři: Silver, Jonathan S, Stumhofer, Jason S., Passos, Sara, Ernst, Matthias, Hunter, Christopher A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3119722/
https://ncbi.nlm.nih.gov/pubmed/21606248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1004144
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