Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA

Lamins A and C, alternatively spliced products of the LMNA gene, are key components of the nuclear lamina. The two isoforms are found in similar amounts in most tissues, but we observed an unexpected pattern of expression in the brain. Western blot and immunohistochemistry studies showed that lamin...

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Bibliografske podrobnosti
Main Authors: Jung, Hea-Jin, Coffinier, Catherine, Choe, Youngshik, Beigneux, Anne P., Davies, Brandon S. J., Yang, Shao H., Barnes, Richard H., Hong, Janet, Sun, Tao, Pleasure, Samuel J., Young, Stephen G., Fong, Loren G.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
PNAS Plus
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289373/
https://ncbi.nlm.nih.gov/pubmed/22308344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111780109
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