Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA

Lamins A and C, alternatively spliced products of the LMNA gene, are key components of the nuclear lamina. The two isoforms are found in similar amounts in most tissues, but we observed an unexpected pattern of expression in the brain. Western blot and immunohistochemistry studies showed that lamin...

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Detalhes bibliográficos
Main Authors: Jung, Hea-Jin, Coffinier, Catherine, Choe, Youngshik, Beigneux, Anne P., Davies, Brandon S. J., Yang, Shao H., Barnes, Richard H., Hong, Janet, Sun, Tao, Pleasure, Samuel J., Young, Stephen G., Fong, Loren G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289373/
https://ncbi.nlm.nih.gov/pubmed/22308344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1111780109
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