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Investigating the purpose of prelamin A processing

Lmna yields two major protein products in somatic cells, lamin C and prelamin A. Mature lamin A is produced from prelamin A by four posttranslational processing steps—farnesylation of a carboxyl-terminal cysteine, release of the last three amino acids of the protein, methylation of the farnesylcyste...

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Detalhes bibliográficos
Main Authors: Davies, Brandon SJ, Coffinier, Catherine, Yang, Shao H, Barnes, Richard H, Jung, Hea-Jin, Young, Stephen G, Fong, Loren G
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3104803/
https://ncbi.nlm.nih.gov/pubmed/21647293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.2.1.13723
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