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The adenylyltransferase domain of bacterial Pnkp defines a unique RNA ligase family

Pnkp is the end-healing and end-sealing component of an RNA repair system present in diverse bacteria from ten different phyla. To gain insight to the mechanism and evolution of this repair system, we determined the crystal structures of the ligase domain of Clostridium thermocellum Pnkp in three fu...

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Detalhes bibliográficos
Main Authors: Smith, Paul, Wang, Li Kai, Nair, Pravin A., Shuman, Stewart
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289333/
https://ncbi.nlm.nih.gov/pubmed/22308407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1116827109
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