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Total Synthesis of the Aminopropyl Functionalized Ganglioside GM(1)
GM1 is a common ganglioside pentasaccharide present on mammalian cell surface. It has been shown to play important roles in cellular communications and initiation of β-amyloid aggregation. In order to synthesize GM1, an efficient synthetic route was developed via a [3+2] strategy. The GM3 trisacchar...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3289147/ https://ncbi.nlm.nih.gov/pubmed/22389646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11426-011-4449-x |
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