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Total Synthesis of the Aminopropyl Functionalized Ganglioside GM(1)

GM1 is a common ganglioside pentasaccharide present on mammalian cell surface. It has been shown to play important roles in cellular communications and initiation of β-amyloid aggregation. In order to synthesize GM1, an efficient synthetic route was developed via a [3+2] strategy. The GM3 trisacchar...

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Detalhes bibliográficos
Main Authors: Sun, Bin, Yang, Bo, Huang, Xuefei
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3289147/
https://ncbi.nlm.nih.gov/pubmed/22389646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11426-011-4449-x
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