Ganglioside GM1 binds to the Trk protein and regulates receptor function.
Several lines of evidence have suggested that ganglioside GM1 stimulates neuronal sprouting and enhances the action of nerve growth factor (NGF), but its precise mechanism is yet to be elucidated. We report here that GM1 directly and tightly associates with Trk, the high-affinity tyrosine kinase-typ...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC41853/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7539142/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.11.5087 |
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