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Calcium Phosphate Nanoparticles with an Asymmetric Lipid Bilayer Coating for siRNA Delivery to the Tumor

Calcium phosphate (CaP) nanoparticles(NP) with an asymmetric lipid bilayer coating have been designed for targeted delivery of siRNA to the tumor. An anionic lipid, dioleoylphosphatydic acid (DOPA), was employed as the inner leaflet lipid to coat the nano-size CaP cores, which entrap the siRNA, such...

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Библиографические подробности
Главные авторы: Li, Jun, Yang, Yang, Huang, Leaf
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288896/
https://ncbi.nlm.nih.gov/pubmed/22056915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2011.10.020
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