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Synthesis and Characterization of Betaine-like Diacyl Lipids: Zwitterionic Lipids with the Cationic Group at the Bilayer Interface

We synthesized and characterized a series of zwitterionic, acetate-terminated, quaternized amine diacyl lipids (AQ). These lipids have an inverted headgroup orientation as compared to naturally occurring phosphatidylcholine (PC) lipids; the cationic group is anchored at the membrane interface, while...

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Detalhes bibliográficos
Main Authors: Kohli, Aditya G., Walsh, Colin L., Szoka, Francis C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288814/
https://ncbi.nlm.nih.gov/pubmed/22301334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chemphyslip.2012.01.005
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