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Requirement of Phospholipase C and Protein Kinase C in Cholecystokinin-mediated Facilitation of NMDA Channel Function and Anxiety-like Behavior

Whereas cholecystokinin (CCK) has long been known to exert anxiogenic effects in both animal anxiety models and humans, the underlying cellular and molecular mechanisms are ill-defined. CCK interacts with CCK-1 and CCK-2 receptors resulting in up-regulation of phospholipase C (PLC) and protein kinas...

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Autors principals: Xiao, Zhaoyang, Jaiswal, Manoj, Deng, Pan-Yue, Matsui, Toshimitsu, Shin, Hee-Sup, Porter, James E., Lei, Saobo
Format: Artigo
Idioma:Inglês
Publicat: 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288799/
https://ncbi.nlm.nih.gov/pubmed/22072552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20984
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