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Phospholipase C not protein kinase C is required for the activation of TRPC5 channels by cholecystokinin

Cholecystokinin (CCK) is one of the most abundant neuropeptides in the brain where it interacts with two G protein-coupled receptors (CCK1 and CCK2). Both types of CCK receptors are coupled to Gq/11 proteins resulting in increased function of phospholipase C (PLC) pathway. Whereas CCK has been sugge...

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Detalhes bibliográficos
Main Authors: Grisanti, Laurel A., Kurada, Lalitha, Cilz, Nicholas I., Porter, James E., Lei, Saobo
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402599/
https://ncbi.nlm.nih.gov/pubmed/22683873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2012.05.032
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