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Requirement of Phospholipase C and Protein Kinase C in Cholecystokinin-mediated Facilitation of NMDA Channel Function and Anxiety-like Behavior
Whereas cholecystokinin (CCK) has long been known to exert anxiogenic effects in both animal anxiety models and humans, the underlying cellular and molecular mechanisms are ill-defined. CCK interacts with CCK-1 and CCK-2 receptors resulting in up-regulation of phospholipase C (PLC) and protein kinas...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3288799/ https://ncbi.nlm.nih.gov/pubmed/22072552 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hipo.20984 |
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