Monohydroxylated metabolites of the K2 synthetic cannabinoid JWH-073 retain intermediate to high cannabinoid 1 receptor (CB1R) affinity and exhibit neutral antagonist to partial agonist activity

Παρόμοια τεκμήρια

• Conjugation of Synthetic Cannabinoids JWH-018 and JWH-073, Metabolites by Human UDP-Glucuronosyltransferases
  ανά: Chimalakonda, Krishna C., κ.ά.
  Έκδοση: (2011)
• Repeated administration of phytocannabinoid Δ(9)-THC or synthetic cannabinoids JWH-018 and JWH-073 induces tolerance to hypothermia but not locomotor suppression in mice, and reduces CB1 receptor expression and function in a brain region-specific manner
  ανά: Tai, S, κ.ά.
  Έκδοση: (2015)
• Human metabolites of synthetic cannabinoids JWH-018 and JWH-073 bind with high affinity and act as potent agonists at cannabinoid type-2 receptors
  ανά: Rajasekaran, Maheswari, κ.ά.
  Έκδοση: (2013)
• Phase I hydroxylated metabolites of the K2 synthetic cannabinoid JWH-018 retain in vitro and in vivo cannabinoid 1 receptor affinity and activity.
  ανά: Lisa K Brents, κ.ά.
  Έκδοση: (2011-01-01)
• Phase I Hydroxylated Metabolites of the K2 Synthetic Cannabinoid JWH-018 Retain In Vitro and In Vivo Cannabinoid 1 Receptor Affinity and Activity
  ανά: Brents, Lisa K., κ.ά.
  Έκδοση: (2011)