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Structural analyses clarify the complex control of mistranslation by tRNA synthetases

Proteins are precisely assembled with amino acids by matching the anticodons of charged transfer RNAs to nucleotide triplets in mRNA sequences. Accurate translation depends on the specific coupling of cognate amino acids and tRNAs – a step carried out by aminoacyl-tRNA synthetases (aaRSs) and that g...

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Détails bibliographiques
Auteurs principaux: Guo, Min, Schimmel, Paul
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288634/
https://ncbi.nlm.nih.gov/pubmed/22155179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2011.11.008
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