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Structural analyses clarify the complex control of mistranslation by tRNA synthetases

Proteins are precisely assembled with amino acids by matching the anticodons of charged transfer RNAs to nucleotide triplets in mRNA sequences. Accurate translation depends on the specific coupling of cognate amino acids and tRNAs – a step carried out by aminoacyl-tRNA synthetases (aaRSs) and that g...

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Detalhes bibliográficos
Main Authors: Guo, Min, Schimmel, Paul
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288634/
https://ncbi.nlm.nih.gov/pubmed/22155179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sbi.2011.11.008
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