Inhibition of Hematopoietic Protein Tyrosine Phosphatase Augments and Prolongs ERK1/2 and p38 Activation

The hematopoietic protein tyrosine phosphatase (HePTP) is implicated in the development of blood cancers through its ability to negatively regulate the mitogen-activated protein kinases (MAPKs) ERK1/2 and p38. Small-molecule modulators of HePTP activity may become valuable in treating hematopoietic...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Sergienko, Eduard, Xu, Jian, Liu, Wallace H., Dahl, Russell, Critton, David A., Su, Ying, Brown, Brock T., Chan, Xochella, Yang, Li, Bobkova, Ekaterina V., Vasile, Stefan, Yuan, Hongbin, Rascon, Justin, Colayco, Sharon, Sidique, Shyama, Cosford, Nicholas D.P., Chung, Thomas D.Y., Mustelin, Tomas, Page, Rebecca, Lombroso, Paul J., Tautz, Lutz
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: 2011
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Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3288537/
https://ncbi.nlm.nih.gov/pubmed/22070201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2004274
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